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目的 进一步提高肾上腺皮质癌的诊治水平。 方法 对 18例经手术证实并有明确病理诊断的肾上腺皮质癌进行回顾性分析。 结果 功能型肿瘤占 5 0 % ,无功能型肿瘤占 5 0 %。手术 15例 ,其中手术全切肿瘤 9例 ,姑息性切除 6例。穿刺活检 3例。本组病例中肿瘤分期 :一期16 7% ,平均存活为 47 3个月 ,5年存活率为 6 6 7% ;二期 16 7% ,平均存活为 37个月。 3年存活率为6 6 7% ;三期 2 2 2 % ,平均存活为 9 8个月 ,1年存活率为 5 0 % ;四期 44 4% ,平均存活为 4 6个月 ,2年存活率为 12 2 %。 结论 外科手术治疗是肾上腺皮质癌唯一有效的治疗方法 ,早期诊断、早期彻底手术是治疗本病的关键。
Objective To further improve the diagnosis and treatment of adrenocortical carcinoma. Methods A retrospective analysis of 18 cases of adrenocortical carcinoma confirmed by surgery and with a clear pathological diagnosis was performed. Results Functional tumors accounted for 50%, non-functional tumors accounted for 50%. Fifteen patients underwent surgery, including 9 cases of total surgical resection and 6 cases of palliative resection. Biopsy in 3 cases. In this group of patients, the tumor stage was: 16 7% in the first phase, the average survival was 47 3 months, the 5-year survival rate was 6 6.7 %, and the second phase was 16 7%. The average survival time was 37 months. The 3-year survival rate was 66.7%; the 3rd stage was 22.2%; the average survival was 98 months; the 1-year survival rate was 50%; the 4-stage 44%; the average survival rate was 46 months and 2 years. The survival rate was 12 2%. Conclusion Surgical treatment is the only effective treatment for adrenocortical carcinoma. Early diagnosis and early thorough surgery are the key to treat this disease.