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骨保护素(osteoprotegerin,OPG)是1997年Tsuda等[1]在人胚胎肺纤维细胞中发现的一种分泌蛋白,是肿瘤坏死因子受体(TNFR)超家族的一员,具有调节骨密度的作用。
Osteoprotegerin (OPG), a secreted protein found in human embryonic lung fibroblasts by Tsuda et al [1] in 1997, is a member of the tumor necrosis factor receptor (TNFR) superfamily and has the ability to regulate bone mineral density effect.