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目的:探讨用奥扎格雷钠治疗急性脑梗死的临床疗效。方法:将我院2009年10月～2011年10月收治的95例急性脑梗死患者随机分成两组。其中一组为对照组,对照组患者应用血塞通注射液进行治疗,另外一组为治疗组,治疗组患者应用奥扎格雷钠注射液进行治疗。3个疗程后,对比两组患者的临床疗效。结果:对照组患者治疗后的神经功能缺失状况较治疗前无显著差异(P>0.05);治疗组患者治疗后的神经功能缺失状况较治疗前有显著性差异(P<0.01);治疗组患者治疗后的神经功能缺失状况较对照组患者好,且两组间的差异具有显著性(P<0.01);治疗组患者的总有效率高于对照组患者,且两组间的差异具有显著性(P<0.01)。结论:应用奥扎格雷钠治疗急性脑梗死可有效改善患者的神经功能、抑制血栓的生成,是一种值得在临床上推广和应用的治疗急性脑梗死的方法。
Objective: To investigate the clinical efficacy of sodium ozagrel in the treatment of acute cerebral infarction. Methods: A total of 95 patients with acute cerebral infarction who were treated in our hospital from October 2009 to October 2011 were randomly divided into two groups. One group was control group, the control group was treated with Xuesaitong injection, and the other group was treated group. Patients in treatment group were treated with ozagrel sodium injection. After 3 courses, the clinical efficacy of the two groups were compared. Results: The neurological deficits in the control group were not significantly different from those before treatment (P> 0.05). The neurological deficits in the treatment group were significantly different from those before treatment (P <0.01). The patients in the treatment group After treatment, the neurological deficit was better than that of the control group, and the difference between the two groups was significant (P <0.01); the total effective rate of the treatment group was higher than that of the control group, and the difference between the two groups was significant (P <0.01). Conclusion: The application of ozagrel sodium in the treatment of acute cerebral infarction can effectively improve the neurological function and inhibit the formation of thrombus in patients with acute cerebral infarction, which is worthy of popularization and application in clinical treatment of acute cerebral infarction.