我们用甲氨喋呤 (MTX)鞘内注射防治中枢神经系统白血病 (CNSL) 2 0 9例次 ,发生神经系统并发症 2 0例次 ,发生率10 .5 % ,现将结果报告如下。1　资料与方法1.1　一般资料　 2 0例次均为住院患者 ,男性 16例 ,女性 4例 ,年龄 13岁～ 71岁 ,平均 34 .5岁。急性白血病 17例 ,按照 We used intraperitoneal injection of methotrexate (MTX) to prevent CNS 209 cases, and 20 cases of neurological complications occurred. The incidence was 10.5%. The results are reported below. 1 Materials and Methods 1.1 General Information 20 cases were hospitalized patients, 16 males and 4 females, aged 13 to 71 years, an average of 34.5 years old. 17 cases of acute leukemia, according to