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肿瘤的发生是癌基因和抑癌基因功能失衡的过程。近年来鉴定出的一类21～25个核苷酸构成的非编码单链小RNA分子(miRNAs,微小RNA),在肿瘤研究中提供了一个新的视野其研究始于1993年发现的第一个miRNAs(1in-4),当时人们认为miRNAs只是在个体发育的时序性渊控方面具有重要作用,而最近的研究显示,许多miRNAs的功能与细胞的增
The occurrence of tumors is a process of imbalance between oncogenes and tumor suppressor genes. In recent years, a class of non-coding single-stranded small RNA molecules (miRNAs, microRNAs) consisting of 21-25 nucleotides have been identified, providing a new field of vision in oncology research. The study began in 1993 with the discovery of the first A few miRNAs (1in-4) were thought to play an important role in temporal sequencing of individual development, and recent studies have shown that the function of many miRNAs is associated with increased cell proliferation