目的探讨胸腹腔镜和三切口手术治疗食管癌的临床疗效比较。方法选取2014年7月至2015年7月间新疆医科大学附属肿瘤医院收治的90例食管癌患者,采用随机数字表法分为胸腹腔镜组与三切口手术组,每组45例。对比两组患者手术时间、术中出血量、淋巴结清扫情况、术后胸腔引流量、术后胸管留置时间、术后监护时间、术后住院时间、住院总费用、术后30天内并发症发生率、术后1年生存率、无病生存率和生活质量。结果胸腹腔镜组手术时间、术中出血量、术后监护时间、术后住院时间、住院总费用和术后30天内并发症发生率分别为(190.45±47.83)min、(89.67±40.23)ml、(5.19±0.34)d、(16.51±3.45)d、(34193.98±450.23)元和8.0%,三切口手术组上述指标分别为(250.93±50.98)min、(224.53±80.34)ml、(7.34±1.09)d、(20.89±4.56)d、(45782.13±598.02)元和20.0%,两组比较,差异均有统计学意义(均P<0.05)。胸腹腔镜组1年生存率和无病生存率分别为84.0%和58.0%,三切口手术组上述指标分别为74.0%和42.0%,两组比较,差异均有统计学意义(均P<0.05)。胸腹腔镜组情绪健康、认知功能、社会功能、躯体功能、癌症对自身的影响、生活满足感和食欲评分分别为(93.23±11.45)分、(93.19±12.34)分、(91.23±10.39)分、(92.20±10.45)分、(93.23±10.89)分、(93.10±11.34)分和(93.90±10.98)分,三切口手术组上述指标分别为(82.67±12.81)分、(82.90±11.79)分、(82.91±10.56)分、(83.19±11.56)分、(82.56±11.19)分、(83.23±12.90)分和(83.29±11.49)分,两组比较,差异均有统计学意义(均P<0.05)。结论胸腹腔镜比三切口手术治疗食管癌的临床效果显著,康复时间短,并发症发生率低,术后1年生存率高,能改善患者生活质量。 Objective To investigate the clinical efficacy of thoracic laparoscopy and triple incision in the treatment of esophageal cancer. Methods Ninety patients with esophageal cancer who were admitted to Cancer Hospital of Xinjiang Medical University from July 2014 to July 2015 were randomly divided into thoracic laparoscopic group and three incision group, 45 cases in each group. Comparisons of operation time, intraoperative blood loss, lymph node dissection, postoperative chest drainage, postoperative chest tube indwelling time, postoperative care time, postoperative hospital stay, hospitalization costs, complications within 30 days after operation Rate, 1-year survival rate, disease-free survival rate and quality of life. Results The operation time, intraoperative blood loss, postoperative monitoring time, postoperative hospital stay, total cost of hospital stay and postoperative complications within 30 days were (190.45 ± 47.83) min, (89.67 ± 40.23) ml , (5.19 ± 0.34) d, (16.51 ± 3.45) d, (34193.98 ± 450.23) Yuan and 8.0% respectively. The above indexes in the three incision groups were (250.93 ± 50.98) min, (224.53 ± 80.34) 1.09) d, (20.89 ± 4.56) d, (45782.13 ± 598.02) yuan and 20.0%, respectively. There was significant difference between the two groups (all P <0.05). The 1-year survival rate and disease-free survival rate in thoracic and laparoscopic group were 84.0% and 58.0%, respectively, and the above indexes were 74.0% and 42.0% respectively in the three incision group. There was significant difference between the two groups (all P <0.05 ). The results of emotional life satisfaction, cognitive function, social function, physical function, cancer on themselves, life satisfaction and appetite of thoracic and laparoscopic group were (93.23 ± 11.45), (93.19 ± 12.34), (91.23 ± 10.39) (92.20 ± 10.45) points, (93.23 ± 10.89) points, (93.10 ± 11.34) points and (93.90 ± 10.98) points respectively. The above indexes were 82.67 ± 12.81, 82.90 ± 11.79, (82.91 ± 10.56), (83.19 ± 11.56), (82.56 ± 11.19) points, (83.23 ± 12.90) points and (83.29 ± 11.49) points respectively. There were significant differences between the two groups <0.05). Conclusion Laparoscopic laparoscopic surgery than three incisions for the treatment of esophageal cancer clinical effect is significant, rehabilitation time is short, the incidence of complications, 1 year survival rate is high, can improve the quality of life of patients.