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凋亡抑制蛋白(IAP)家族首先由Crook等[1]发现,是一类新的独立于B型淋巴瘤细胞因子2(Bcl-2)家族的抗凋亡蛋白。细胞凋亡是由多种因子介导的细胞主动死亡的过程,对机体或组织维持内环境的稳定和生物体的生长发育、生命周期、衰老死亡都有着重要的作用。凋亡抑制也是肿瘤发生的重
Apoptosis-inhibiting protein (IAP) family was first identified by Crook et al [1] as a novel class of anti-apoptotic proteins that are independent of the Bcl-2 family. Apoptosis is a process of active cell death mediated by a variety of factors and plays an important role in the maintenance of the internal environment and the growth and development, life cycle and aging of the organism or tissue. Apoptosis is also a tumor weight