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目的:了解、分析我院抗菌药的使用情况,评价用药合理性,为临床用药提供参考。方法:随机抽取2007年度门急诊处方,对抗菌药使用频度(DDDs)及类别进行排序,并对抗菌药处方分类统计,分析用药合理性。结果:DDDs排序前3位为奥硝唑、左氧氟沙星、阿奇霉素;头孢菌素类、喹诺酮类、大环内酯类为最常用的3类抗菌药。共审计处方10 800张,其中抗菌药处方3 842张,不合理处方409张,分别在药物溶媒使用、给药方案、药理作用以及合理用药方面存在问题。结论:我院门急诊抗菌药的使用基本合理,但仍存在某些问题,需进一步改进提高。处方审核将有助于抗菌药的合理使用。
Objective: To understand and analyze the use of antibacterials in our hospital, to evaluate the rationality of drugs and provide reference for clinical use. Methods: Randomized 2007 outpatient and emergency department prescriptions, antimicrobial frequency (DDDs) and categories were sorted, and antimicrobial prescriptions statistics, analysis of drug rationality. Results: The top 3 DDDs were ornidazole, levofloxacin and azithromycin; cephalosporins, quinolones and macrolides were the most commonly used 3 kinds of antibacterials. A total of 10 800 prescriptions were audited, among which 3 842 were antibacterial prescriptions and 409 were unreasonable prescriptions, respectively, which posed problems in the use of drug vehicles, drug regimens, pharmacological effects and rational drug use. Conclusion: The use of outpatient and emergency department antibacterial drugs in our hospital is basically reasonable, but some problems still exist, which needs further improvement and improvement. Prescription review will help rational use of antimicrobial agents.