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腹主动脉瘤(Abdominal Aortic Aneurysm,AAA)发病率男女的比为8∶1,所以引起推测象血友病那样通过X染色体的突变传代的.X染色体的很多基因在哺乳动物和人是相应的.X染色体在进化史已存在一亿年.从X染色体守恒原理,假若一种动物的突变发生在x的基因,则其他动物发生突变时亦将发生在X染色体.作者们发现几个伴性的(X-linked)AAA隐性遗传家族史.本文报告16个家族41例的分析,表示至少有二个或三个遗传的机制.第一组5个家族显然是伴性的显性遗传.如为隐
Abdominal Aortic Aneurysm (AAA) has a ratio of 8: 1 for the incidence of men and women, leading to the speculation that many genes of the X chromosome pass through mutations in the X chromosome, as in hemophilia, in mammals and humans X chromosome has been in the evolutionary history of 100000000 years from the principle of conservation of X chromosomes, if an animal mutation occurs in the x gene, mutation occurs in other animals will also occur in the X chromosome.The authors found several partners (X-linked) family history of AAA recessive inheritance.This article reports the analysis of 41 families in 16 families, indicating that there are at least two or three genetic mechanisms.The first five families are apparently coherent dominant heritability. If hidden