目的:通过探讨中成药临床应用时的不良反应和应对措施,旨在为临床合理用药提高用药安全性提供理论依据。方法:选择2013年1月-2014年1月应用中成药发生不良反应的患者182例,对其临床资料和不良反应表现情况进行总结分析,并针对不同临床表现给予相应治疗和护理对策。结果:中成药临床应用的不良反应主要有过敏反应、神经系统反应、呼吸系统反应、循环系统反应及消化系统不良反应。应对不良反应的措施主要有预防和治疗,通过用药前全面掌握患者体质合理搭配药物,在出现不良反应时快速救治,同时应加强用药知识教育和监管并提高药师业务能力。结论:中成药临床应用可能导致过敏反应等多种不良反应,临床应加强用药知识的宣传和药师素质及建立完善的预防和治疗体系,提高中成药的用药安全。 Objective: To explore the clinical application of proprietary Chinese medicines when adverse reactions and coping strategies aimed at rational use of drugs to improve drug safety to provide a theoretical basis. Methods: One hundred and eighty-two patients with adverse reactions of proprietary Chinese medicines were selected from January 2013 to January 2014. The clinical data and adverse reactions were analyzed and analyzed. Corresponding treatment and nursing strategies were given for different clinical manifestations. Results: The main clinical adverse reactions of proprietary Chinese medicines were allergic reaction, nervous system reaction, respiratory reaction, circulatory system reaction and adverse reaction of digestive system. The main measures to deal with adverse reactions are prevention and treatment, through the medication before a comprehensive grasp of the patient’s physique with drugs, rapid response in the event of adverse reactions, should also strengthen the education and supervision of drug use and improve pharmacist business skills. Conclusion: The clinical application of proprietary Chinese medicines may lead to many adverse reactions such as anaphylaxis. The publicity on the use of medical knowledge and the quality of pharmacists should be strengthened and a sound prevention and treatment system should be established to improve the medication safety of proprietary Chinese medicines.