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患者女性,37岁。右足跟因鞋子摩擦破溃出血1月余,愈合后皮下出现一个暗紫色的斑块状新生物,遂来我院门诊就诊,给予手术切除。病理检查巨检:小块带皮肤组织,0.5 cm×0.5 cm×0.4 cm大小;切面暗红色。镜检:病变位于真皮的网状层内,由增生的不规则形毛细血管型血管结节组成(图1),结节周边可见扩张成新月形的血管腔,结节呈炮弹头样向腔内突起(图2),结节内毛细血管管腔原始、不明显,主要由增生的短梭形血管内皮细胞和血管周细胞组成(图3)。免疫组化:血管内皮细胞CD34(+)(图4),血管周细胞SMA(+)(图5)。
Patient female, 37 years old. Right heel due to friction and ulceration of shoes more than 1 month after healing, subcutaneous emergence of a dark purple patchy new creatures, then came to our hospital clinic, given surgical resection. Histopathological examination: a small piece of skin tissue, 0.5 cm × 0.5 cm × 0.4 cm size; section dark red. Microscopic examination: The lesion is located in the reticular layer of the dermis, composed of hyperplastic irregular capillary vascular nodules (Figure 1), visible around the nodules into a crescent-shaped vascular lumen, nodules were projectile oriented Intraluminal protuberances (Figure 2), nodular capillary lumen primitive, not obvious, mainly by the proliferation of short spindle-shaped vascular endothelial cells and perivascular cells (Figure 3). Immunohistochemistry: Vascular endothelial cells CD34 (+) (Figure 4), perivascular cells SMA (+) (Figure 5).