Foot-and-mouth disease is one of the major contagious zoonotic diseases in the world.It is caused by various species of the genus Aphthovirus of the family Picornavirus,and it always brings a large number of infections and heavy financial losses.The disease has become a major public health concern.In this paper,we propose a nonlocal foot-and-mouth disease model in a spatially heterogeneous environment,which couples virus-to-animals and animals-to-animals transmission pathways,and investigate the dynamics of the disperal.The basic reproduction number R0 is defined as the spectral radius of the next generation operator R(x) by a renewal equation.The relationship between R0 and a principal eigenvalue of an operator L0 is built.Moreover,the proposed system exhibits threshold dynamics in terms of R0,in the sense that R0 determines whether or not foot-and-mouth disease invades the hosts.Through numerical simulations,we have found that increasing animals' movements is an effective control measure for preventing prevalence of the disease.