泛素化作为植物体内一种广泛存在的调控细胞反应的机制,参与调控植物抗病反应。本文综述了泛素化系统在植物抗病反应中的功能及作用机制,重点介绍了CRLs型E3泛素连接酶和RING/U-box型E3泛素连接酶如何参与调控植物抗病信号途径,以及病原物通过效应蛋白和毒性因子调控植物抗病性的分子机理,为阐明植物抗病机理和植物病害防治方法提供参考。 Ubiquitination, as a widely existing mechanism regulating cellular responses in plants, is involved in the regulation of disease resistance in plants. This review summarizes the function and mechanism of ubiquitin system in plant resistance to disease and focuses on how CRLs E3 ubiquitin ligases and RING / U-box E3 ubiquitin ligases are involved in the regulation of disease resistance signaling in plants, As well as the molecular mechanism of pathogen regulation of plant disease resistance by effector proteins and virulence factors, to provide references for elucidating the mechanism of plant disease resistance and plant disease prevention and treatment.