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目的:观察Rh(D)阴性孕妇妊娠晚期预存式自体输血的应用效果。方法:对37例Rh(D)阴性孕妇在围产期前1~3周进行自体血采集1~2次,每次采血200ml,置4℃贮血冰箱内保存备用。对孕妇采血前后及血液回输前后进行红细胞(RBC)、血红蛋白(Hb)、血细胞比容(Hct)、血小板计数(PLT),并观察自体血采集及回输过程中孕妇不良反应和新生儿Apgar评分。结果:37例妊娠晚期Rh(D)阴性孕妇自体血液采集前后3d的RBC、Hb、Hct、PLT结果,差异均无统计学意义(均P>0.05),其中13例自体血液回输的孕妇血液回输前后3d的RBC、Hb、Hct、PLT等指标比较差异无统计学差异(P>0.05);自体血采集及回输过程中孕妇无严重不良反应,均未输注异体血,新生儿Apgar评分为9~10分。结论:预存式自体输血操作简单、安全、能缓解稀有血型血源紧缺等,具有一定的临床推广应用价值。
Objective: To observe the effect of pre-stored autologous blood transfusion in late pregnancy in Rh (D) negative pregnant women. Methods: Thirty-seven Rh (D) negative pregnant women were collected autologous blood 1 ~ 2 times before perinatal period, 200ml each time, stored in refrigerator at 4 ℃ for later use. Red blood cells (RBC), hemoglobin (Hb), hematocrit (Hct) and platelet count (PLT) were measured before and after blood collection and blood transfusion in pregnant women. Adverse reactions of pregnant women during autologous blood collection and reinfusion and neonatal Apgar score. Results: There were no significant differences in RBC, Hb, Hct and PLT between the 37 pregnant women with Rh (D) negative pregnancy before and after autologous blood collection (all P> 0.05), of which 13 were blood transfusions There was no significant difference in RBC, Hb, Hct, PLT and other indexes before and after the transfusion (P> 0.05). There was no serious adverse reactions in pregnant women during autologous blood collection and transfusion, The score is 9 to 10 points. Conclusion: Prefilled autologous blood transfusion is simple, safe and can alleviate scarce blood type in rare blood. It has certain clinical application value.