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阿糖腺苷-5′-磷酸酯是一水溶性抗病毒剂,供注射给药。本文研究本品在水溶液中稳定时的最适pH。动力学研究方法:精确秤取约250mg 的阿糖腺苷-5′磷酸二钠盐,用缓冲液溶解至50ml,混匀。每份5ml,立即灌封于10支为一组的15ml 玻璃安瓿中,置99℃蒸汽浴内,间隔适当时间后,取出安瓿,冷至室温。取
Vidarabin-5’-phosphate is a water-soluble anti-viral agent for injection. This article studies the optimum pH of the product when it is stable in aqueous solution. Kinetic research methods: Accurate weighing about 250mg of adenosine 5 ’phosphate disodium salt, dissolved in 50ml buffer, and mix. Each 5ml, immediately potted in a group of 10 15ml glass ampoules, set 99 ℃ steam bath, after an appropriate interval, remove the ampoule, cooled to room temperature. take