1例69岁男性患者给予注射用单硝酸异山梨酯治疗冠心病。在静脉滴注第5分钟患者由卧位转为坐位时出现头晕、恶心、呕吐、面色潮红、血压急剧下降。立即停用该药,给予升压、扩容等支持治疗并进行心电监测指标。患者头晕、恶心、呕吐等症状逐渐减轻至消失。 A 69-year-old male patient was given isosorbide mononitrate for the treatment of coronary heart disease. In the first 5 minutes of intravenous drip patients turn from sitting to sitting position, dizziness, nausea, vomiting, flushing, blood pressure dropped sharply. Immediate withdrawal of the drug, to give boost, dilatation and other supportive treatment and ECG monitoring indicators. Patients dizziness, nausea, vomiting and other symptoms gradually reduced to disappear.