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作者用ELISA检测108例肝炎患者发现:急性黄疸型、慢性活动型、重症型患者IL-6、IL-8均明显高于对照组;三型间的IL-6有明显差异;IL-8水平重症型明显高于急、慢型;IL-6、IL-8与ALT呈明显正相关; HBeAg(+)组, HBV-DNA(+)组较阴性组IL-6水平明显高,阳性转阴性者IL-6、IL-8水平明显下降;IL-6与IL-8呈明显正相关,表明:IL-6、IL-8参与乙型肝炎患者的免疫病理损伤,其水平可作为判定炎症活动程度和治疗效果的指标。
The authors used ELISA to detect 108 cases of hepatitis patients found: acute jaundice, chronic active type, severe type of IL-6, IL-8 were significantly higher than the control group; IL-6 between the three types were significantly different; IL-8 levels IL-6 and IL-8 were positively correlated with ALT; IL-6 levels in HBeAg (+) group and HBV-DNA (+) group were significantly higher than those in negative group IL-6 and IL-8 showed a significant positive correlation, indicating that: IL-6, IL-8 involved in hepatitis B patients with immunopathological damage, the level can be used as a marker of inflammatory activity Degree and therapeutic effect of the indicators.