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羟丙甲纤维素(hypromellosem,HPMC)是具有优良性能的羟丙基与甲基以醚键连接的纤维素衍生物,为类白色纤维状粉末,在水中溶解形成澄明具有粘性的胶体溶液。此特性大大增加了它在制剂中的应用空间。该产品与多数药物不产生反应,是一种中性的并对人体无害的纤维素衍生物。 混悬型液体制剂是临床上的常用剂型,为难溶性固体药物分散在液体分散介质中形成的非均相分散体系。该体系的稳定性决定了混悬型液体制剂质
Hypromellose (HPMC) is a cellulose derivative with excellent properties of hydroxyl propyl group and methyl group connected by ether bond. It is a white fibrous powder that dissolves in water to form a clear and viscous colloidal solution. This feature greatly increases its application space in the formulation. The product does not react with most drugs, is a neutral and harmless to human body cellulose derivatives. Suspension-type liquid formulations are clinically usual dosage forms for the formation of heterogeneous dispersions of sparingly soluble solid drugs dispersed in a liquid dispersion medium. The stability of the system determines the quality of the suspension liquid formulation