左氧氟沙星相关精神障碍

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1例40岁女性因患慢性支气管炎急性发作和阻塞性肺气肿,给予左氧氟沙星0.2 g,2次/d静滴;甘草片4片,3次/d;鲜竹沥液20 ml,3次/d;茶碱缓释片(0.2 g)1片,2次/d治疗。第2天,患者出现行为异常,幻视,幻听。除外肺性脑病和茶碱中毒,考虑精神障碍与左氧氟沙星有关。停用左氧氟沙星,给予抗精神病药物治疗,2 d后患者症状消失。 One 40-year-old woman suffered from acute exacerbation of chronic bronchitis and obstructive pulmonary emphysema. The patients were given 0.2 g levofloxacin twice daily intravenously, 4 tablets of licorice root, 3 times daily and 20 ml of fresh bamboo leachate, 3 times / d; theophylline sustained release tablets (0.2 g) 1, 2 times / d treatment. The first 2 days, patients with abnormal behavior, visual hallucinations, auditory hallucinations. In addition to pulmonary encephalopathy and theophylline poisoning, consider mental disorders and levofloxacin. Levofloxacin was discontinued and antipsychotic drugs were given, and symptoms disappeared after 2 days.
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