HIV still remains a global public health problem despite decades of interventions to eliminate the virus.In 2010,there were 390 000 children globally,under 15 years old,newly infected with HIV,mainly through mother-to-child transmission.1 China had 780 000 HIV infected people at the end of 2011,of these,28.6％ were women and 1.1％ were children infected through mother-to-child transmission.2 The first case of mother-to-child transmission (MTCT) of HIV in China was reported in 1995.3 Few years later,the proportion of MTCT in China increased from 0.1％ in 1997 to 0.4％ in 2002.4 The Ministry of Health in China in conjunction with the Central for Matal and Child Healthcare and the Chinese Centre for Disease Control launched prevention of mother-child transmission of HIV (PMTCT) programs in China in 2003.The programs were launched in five provinces with high prevalence of HIV namely,Henan,Guangdong,Yunnan,Guangxi and Xinjiang.