目的:研究血必净在脓毒症患者毛细血管渗漏综合征的应用效果。方法:64例患者随机分为2组。对照组30例采取常规治疗措施;治疗组34例在对照组治疗基础上加用血必净治疗。治疗7天。比较2组治疗后血清C-反应蛋白(CRP)、血栓调节蛋白(TM)、血清肌酐(SCr)、总胆红素(TBil)水平;记录2组患者的住院时间、机械通气时间以及病死率。结果:治疗后治疗组CRP、TM、SCr及TBil水平显著改善,与对照组比较,差异有统计学意义(P<0.05)。治疗组住院时间、机械通气时间及病死率与对照组比较,差异有统计学意义(P<0.05)。结论:血必净在脓毒症患者毛细血管渗漏综合征中疗效好,明显改善患者症状与体征,死亡率低。 Objective: To study the effect of Xuebijing in the treatment of capillary leak syndrome in sepsis patients. Methods: 64 patients were randomly divided into two groups. Control group of 30 patients take conventional treatment; 34 cases of treatment group in the control group based on the use of Xuebijing treatment. Treatment for 7 days. The levels of C-reactive protein (CRP), thrombomodulin (TM), serum creatinine (SCr) and total bilirubin (TBil) were compared between the two groups. The length of hospital stay, . Results: After treatment, the levels of CRP, TM, SCr and TBil in the treatment group were significantly improved compared with the control group (P <0.05). Treatment group hospitalization time, mechanical ventilation time and mortality compared with the control group, the difference was statistically significant (P <0.05). Conclusion: Xuebijing has a good curative effect in capillary leak syndrome in patients with sepsis, and obviously improves the symptoms and signs of patients with low mortality.