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目的探讨维吾尔族人群中高尿酸血症患病率及其相关因素。方法对新疆维吾尔自治区乌鲁木齐市二道桥片区居民采用整群随机抽样,抽取1 302名居民,进行问卷调查、体格检查和实验室检查,了解维吾尔族人群高尿酸血症患病率并分析其相关因素。结果对1 302名居民完成调查,其中男592名,女710名,尿酸水平为(235.85±77.06)μmol/L,高尿酸血症患病率为1.9%。男性各年龄段患病率比较差异有统计学意义(P<0.05),女性各年龄段患病率比较差异无统计学意义(P>0.05),男性患病率略高于女性。回归分析显示,性别、舒张压、腰围、甘油三酯、总胆固醇、低密度脂蛋白、高密度脂蛋白、体重指数、空腹血糖与高尿酸血症密切相关(P<0.05)。结论新疆维吾尔自治区乌鲁木齐市维吾尔族高尿酸血症水平较低。腰围、体重指数、低密度脂蛋白、甘油三酯、胆固醇、空腹血糖是高尿酸血症的危险因素,高密度脂蛋白是高尿酸血症的保护因素。
Objective To investigate the prevalence of hyperuricemia in Uighur population and its related factors. Methods Residents of Erdaoqiao district of Urumqi, Xinjiang Uygur Autonomous Region were randomly selected by cluster sampling, and 1 302 residents were sampled for questionnaires, physical examinations and laboratory tests to understand the prevalence of hyperuricemia in Uyghur people and to analyze their correlation factor. Results A total of 1 302 residents were investigated, including 592 males and 710 females, with a mean uric acid level of (235.85 ± 77.06) μmol / L and a prevalence of hyperuricemia of 1.9%. The prevalence of men in all age groups was significantly different (P <0.05). There was no significant difference in the prevalence among all age groups (P> 0.05). The prevalence of male was slightly higher than that of female. Regression analysis showed that gender, diastolic blood pressure, waist circumference, triglyceride, total cholesterol, low density lipoprotein, high density lipoprotein, body mass index, fasting blood glucose and hyperuricemia were closely related (P <0.05). Conclusions Uyghur people have lower level of hyperuricemia in Urumqi, Xinjiang Uygur Autonomous Region. Waist circumference, body mass index, low density lipoprotein, triglyceride, cholesterol, fasting blood glucose are the risk factors of hyperuricemia. High density lipoprotein is the protective factor of hyperuricemia.