紫杉醇是国际上90年代的抗癌新药,临床用于治疗转移性卵巢癌和乳腺癌。由于这一药物的作用机理不同于其他细胞毒类抗癌药,遂引起国际上医药界的关注。近年的研究表明,紫杉醇对肺癌和颈部肿瘤也有效,更引起医药界重视。 紫杉醇在国外最初是用红豆杉树皮为原料,经提取精制而得。由于在树皮中的含量较低,提取分离的技术比较 Paclitaxel is an international anti-cancer drug in the 90’s. It is used clinically to treat metastatic ovarian cancer and breast cancer. As the mechanism of action of this drug is different from other cytotoxic anticancer drugs, it has aroused the concern of the international pharmaceutical community. In recent years, studies have shown that paclitaxel is also effective in lung cancer and neck cancer, but also caused the medical community attention. Paclitaxel was originally used abroad as a raw material of bark of Taxus, derived by extraction. Due to the low content in the bark, extraction and separation techniques are compared