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本文采取随机、双盲、安慰剂对照的多中心试验,评价了法昔洛韦对无并发症的急性带状癌疹(AHZ)和AHZ后神经痛的疗效与安全性。所有患者均在瘤疹性皮疹发病72小时内用法昔洛韦500、750mg或安慰剂治疗7天,一日3次。1方法419例患者中,法昔洛韦500mg和750mg组分别为135例和135
This randomized, double-blind, placebo-controlled, multicenter trial evaluated the efficacy and safety of famciclovir in the treatment of uncomplicated AHZ and post-AHZ neuropathic pain. All patients were treated with either famciclovir 500, 750 mg or placebo for 72 days, three times daily, within 72 hours of onset of the rash episode. 1 Methods Among 419 patients, 135 and 135 were assigned to the famciclovir 500 mg and 750 mg groups, respectively