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目的评价当归阿胶口服液改善缺铁性贫血的效果。方法选雌性断乳大鼠80只,以低铁饲料喂养造模后选血红蛋白(Hb)<100 g/L的个体,按Hb水平分层随机分为低铁对照组和3个试验组,每组12只大鼠。设试验剂量为5.00、2.50、1.25 ml/kg.bw,低铁对照组给予去离子水。每日1次经口灌胃给样,试验周期42 d。试验终末测定大鼠Hb和红细胞内游离原卟啉(FEP)含量。结果与低铁对照组相比较,各剂量组大鼠Hb含量显著上升,FEP含量显著降低。结论当归阿胶口服液有改善缺铁性贫血的作用。
Objective To evaluate the effect of Angelica Ejiao oral liquid on iron deficiency anemia. Methods Totally 80 female weanling rats were fed with low iron diet, and those with hemoglobin (Hb) <100 g / L were randomly divided into low iron control group and 3 experimental groups according to Hb level. Groups of 12 rats. Set the test dose of 5.00,2.50,1.25 ml / kg.bw, low iron control group given deionized water. 1 times a day by oral gavage, the test period of 42 d. At the end of the experiment, the levels of Hb and erythrocyte free protoporphyrin (FEP) were determined. Results Compared with the low-iron control group, the Hb content of each dose group increased significantly and the FEP content decreased significantly. Conclusion Angelica Jiao oral solution to improve iron deficiency anemia.