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目的了解女性生殖道人乳头状瘤病毒(HPV)感染状况。方法对2010年8月-2012年8月在我院进行宫颈病变筛查的2100例患者,采用聚合酶链反应(PCR)-寡核苷酸微流芯片进行HPV分型检测。结果 HPV感染总阳性率27%(567/2100),高危型HPV感染率498/2100(23.7%),低危型HPV感染率69/2100(3.3%)。结论我院就诊妇女感染HPV16、52、58、cp8304、53、18、33、66为主,HPV检测对宫颈病变的筛查与诊断具有一定价值,可为宫颈癌的防治提供流行病学数据。
Objective To understand the female genital tract human papilloma virus (HPV) infection. Methods 2100 cases of cervical lesions screening in our hospital from August 2010 to August 2012 were genotyped by polymerase chain reaction (PCR) - oligonucleotide microarray. Results The total positive rate of HPV infection was 27% (567/2100), high-risk HPV infection rate was 498/2100 (23.7%), and low-risk HPV infection rate was 69/2100 (3.3%). Conclusion The prevalence of HPV16,52,58, cp8304,53,18,33,66 infection in women in our hospital is mainly high. HPV testing has some value in the screening and diagnosis of cervical lesions, which can provide epidemiological data for the prevention and treatment of cervical cancer.