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探讨蛋白酶ICH与慢性乙型肝炎的关系。采用免疫组化技术研究蛋白酶ICH在33例慢性乙型肝炎组织中的表达。结果表明慢迁肝和慢活肝中ICH-IL及ICH-1S阳性率较正常肝增加,但无明显差异;而坏死区肝细胞的阳性信号明显强于其他区域肝细胞和正常肝细胞。结论ICH-1可能参与肝细胞的损伤过程。
To explore the relationship between protease ICH and chronic hepatitis B Immunohistochemistry was used to study the expression of protease ICH in 33 chronic hepatitis B patients. The results showed that the positive rates of ICH-IL and ICH-1S in slow-moving and slow-moving liver were higher than those in normal liver, but there was no significant difference. The positive signals of hepatocytes in necrotic area were obviously stronger than those in other areas. Conclusion ICH-1 may be involved in the process of hepatocyte injury.