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在长期随访乳头状甲状腺病人中，由于人口背景、肿瘤生物学行为以及诊疗方法的改变，总结时要考虑这些因素。作者分析1965～1990年的乳头状甲状腺癌手术病人的不同人口背景、治疗、预后和危机因素。日本Oita大学甲状腺临床中心在25年中，曾收治乳头状甲状腺癌3426例，除去861例
In the long-term follow-up of patients with papillary thyroid, due to changes in population background, tumor biological behavior, and diagnosis and treatment methods, these factors should be taken into account when summarizing. The authors analyzed different population background, treatment, prognosis, and crisis factors for patients with papillary thyroid cancer from 1965 to 1990. In the 25th year of Oita University’s thyroid clinical center in Japan, 3426 cases of papillary thyroid cancer were treated and 861 cases were removed.