目的:探讨强心胶囊治疗老年高血压并左室射血分数正常型心力衰竭(HFNEF)的临床疗效。方法:将63例老年高血压并HFNEF患者按随机分层分组法分为对照组和观察组,对照组患者采用西医常规治疗,观察组患者在对照组基础上给予强心胶囊口服,观察两组患者在治疗前后心功能、血压、B型钠尿肽(BNP)及6 min步行距离(6-MWD)变化情况。结果:两组患者经治疗后均较治疗前各项观察指标有明显改善,差异具有统计学意义(P<0.01)。观察组患者血压控制情况优于对照组,但观察组治疗后各项指标与对照组比较,差异均无统计学意义(P>0.05);观察组患者在BNP及6-MWD指标均优于对照组,差异有统计学意义(P<0.05)。观察组患者临床总有效率为87.87%(29/33),对照组患者临床总有效率为66.66%(20/30),两组比较,差异有统计学意义(P<0.05)。结论:强心胶囊可以协同西药提高治疗老年高血压并HFNEF患者的临床疗效,降低BNP水平,明显增加6-MWD。 Objective: To investigate the clinical effect of Qiangxin Capsule in the treatment of elderly patients with hypertension and left ventricular ejection fraction normal heart failure (HFNEF). Methods: Sixty-three hypertensive patients with HFNEF were randomly divided into control group and observation group according to randomized stratified group method. Patients in control group were treated with conventional western medicine. Patients in observation group were given Qiangxin capsule orally on the basis of control group. The changes of cardiac function, blood pressure, BNP and 6-MWD in patients before and after treatment. Results: The two groups of patients after treatment were significantly improved than before treatment of various indicators, the difference was statistically significant (P <0.01). The blood pressure control in the observation group was better than that in the control group, but there was no significant difference between the observation group and the control group (P> 0.05). The BNP and 6-MWD indexes in the observation group were better than those in the control group Group, the difference was statistically significant (P <0.05). The total clinical effective rate was 87.87% (29/33) in the observation group and 66.66% (20/30) in the control group. The difference between the two groups was statistically significant (P <0.05). CONCLUSION: Qiangxin capsule can improve the clinical curative effect of treatment of elderly patients with hypertension and HFNEF in combination with western medicine, reduce the level of BNP and increase 6-MWD obviously.