急性早幼粒细胞白血病是一种相对少见的疾病,依其细胞形态可分为粗颗粒型和细颗粒型两种。一些研究表明M3有非典型的酯酶染色,粗颗粒型尤其如此,有些学者认为这是由于混合性粒-单核细胞分化所致。本文对44例M3患者(其中粗颗粒型30例,细颗粒型14例)进行了免疫学和酶学研究。 30例粗颗粒型M3均为髓过氧化物酶(MPO)和氯乙酸酯酶(CE)强阳性,其中20例α-醋酸萘酯酶(ANAE)阳性细胞比例为18-85%,中数为62%,7例弱阳性,13例中度至强阳 Acute promyelocytic leukemia is a relatively rare disease. According to its cell morphology, it can be divided into two types: coarse-grained and fine-grained. Some studies show that M3 has atypical esterase staining, especially for coarse-grained particles, which some scholars believe is due to mixed granulocyte-monocyte differentiation. In this paper, 44 cases of M3 patients (including 30 cases of coarse-grained type and 14 cases of fine-grained type) were studied immunologically and enzymologically. 30 cases of coarse-granular M3 were strongly positive for myeloperoxidase (MPO) and chloroacetate esterase (CE), and 20 cases of α-acetate naphthylase (ANAE) positive cells accounted for 18-85%. 62%, 7 weakly positive, 13 moderate to strong