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目的研究延长输注碳青酶烯类抗生素和哌拉西林他唑巴坦在重症监护病区中推广应用的可行性。方法医药护多学科合作,对重症监护病区使用美罗培南、比阿培南和哌拉西林他唑巴坦的患者应用延长输注时间的给药方案,记录并评估新方案实施的效果及遇到的问题。结果在6个月的临床实践中,有56例患者使用微泵延长抗菌药物输注时间,占总用药例数的61.5%。没有使用新方案的原因主要有医师习惯按旧方案开医嘱;患者静脉输液通道有限等。实施过程中发现的问题主要有同时输注药物不兼容,微量注射泵设置错误等。结论应用微泵延长抗菌药物输注时间的给药方案可以在重症患者中应用,但是需要医药护多学科团队的密切配合,尤其需要药师的严密监督以保证患者的用药安全有效。
Objective To investigate the feasibility of extending the application of carbapenem antibiotics and piperacillin-tazobactam in intensive care unit. Methods Multidisciplinary cooperation in medical care, intensive care unit using meropenem, biapenem and piperacillin tazobactam patients to extend the infusion time of the dosing regimen, record and evaluate the effectiveness of the new program and in case To the question. Results In 6 months of clinical practice, 56 patients used micro-pumps to prolong the infusion time of antibiotics, accounting for 61.5% of the total drug use cases. The reasons for not using the new scheme are mainly physicians accustomed to the doctor according to the old program; patients with limited venous infusion channels. Problems found during the implementation of the main infusion of drugs are not compatible, micro-injection pump set the wrong. Conclusion The application of micropumps to prolong the infusion time of antimicrobial agents can be used in patients with severe diseases. However, it requires the close cooperation of multidisciplinary team of medical care. In particular, strict supervision by pharmacists is required to ensure the safety and effectiveness of the medication.