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本文应用GO-Schiff对76例大肠腺癌、68例大肠腺瘤、15例增生性息肉、5例溃疡性结肠炎及30例正常肠粘膜的组织切片和直肠粘液中的肿瘤标记物(T抗原)进行同步检测,其各组检出率依次为81.6%和89.5%,79.4%和67.6%,40.6%和20.0%。60.0和20.0%及0和10.0%,提示GO-Schiff试剂作为筛检大肠癌指标具有一定的可信性,同时,观察大肠癌组织切片中T抗原的定位分布与癌细胞的分化程度有关。分析GO-Schiff试验对大肠癌及癌前病变,无论在组织切片还是直肠粘液水平均为较特异的筛检方法之一。
In this paper, GO-Schiff was used to identify 76 cases of colorectal adenocarcinoma, 68 cases of colorectal adenoma, 15 cases of hyperplastic polyp, 5 cases of ulcerative colitis, and 30 cases of normal intestinal mucosa. Tumor markers (T antigen) in rectal mucus ) In the simultaneous detection, the detection rates of each group were 81.6% and 89.5%, 79.4% and 67.6%, 40.6% and 20.0%, respectively. 60.0 and 20.0% and 0 and 10.0%, suggesting that GO-Schiff reagent as a screening indicator of colorectal cancer has a certain degree of credibility, at the same time, observe the localization of T antigen in colorectal cancer tissue slices and the degree of differentiation of cancer cells. The GO-Schiff test was one of the more specific screening methods for colorectal cancer and precancerous lesions, both in the tissue section and rectal mucus level.