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目的探讨在临床急性冠脉综合征中应用钙离子拮抗剂的疗效。方法选取2014年11月~2015年11月本院收治的急性冠脉综合征患者62例作为研究对象,将其随机分为对照组和观察组,各31例。对照组给予针对性药物治疗,观察组采用钙离子拮抗剂氨氯地平联合缬沙坦治疗,并对比两组的疗效。结果观察组总有效率为96.8%,高于对照组的74.2%,差异有统计学意义(P<0.05)。结论钙离子拮抗剂治疗临床急性冠脉综合征的疗效优良,可有效缓解心绞痛症状,且不良反应少,安全性高,值得临床推广。
Objective To investigate the efficacy of calcium antagonists in clinical acute coronary syndromes. Methods Sixty-two patients with acute coronary syndrome admitted to our hospital from November 2014 to November 2015 were selected as the research object, which were randomly divided into control group and observation group, with 31 cases in each group. The control group was given targeted drug therapy. The observation group was treated with amlodipine combined with valsartan, a calcium ion antagonist. The curative effect was compared between the two groups. Results The total effective rate of observation group was 96.8%, which was higher than that of control group (74.2%), the difference was statistically significant (P <0.05). Conclusion Calcium antagonists are effective in treating acute coronary syndromes, which can relieve the symptoms of angina pectoris, with less adverse reactions and high safety. It is worthy of clinical promotion.