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以间苯三酚为原料,经九步反应合成血竭素(1)及其高氯酸盐(1')。改进了2,6-二羟基-4-甲氧基苯甲酸甲酯(4)及2,6-二羟基-3-甲酰-4-甲氧基苯甲酸甲酯(5)的制备方法。
With phloroglucinol as raw material, nine steps of the reaction of the synthesis of dracorhodin (1) and its perchlorate (1 ’). The preparation of methyl 2,6-dihydroxy-4-methoxybenzoate (4) and methyl 2,6-dihydroxy-3-formyl-4-methoxybenzoate (5) were improved.