论文部分内容阅读
目的:观察米非司酮治疗子宫肌瘤的临床效果。方法:选取我院收治的子宫肌瘤患者60例,给予其口服米非司酮的方式进行治疗,具体的用药剂量为10mg/次,1次/d,连续用药3个月。对比患者用药前后,彩超和超声检测下的子宫肌瘤大小。结果:经过用药治疗之后,60例患者的临床症状均消失、血红蛋白恢复正常、且均出现闭经现象。60例患者子宫体积平均缩小了40.80%(P<0.01),患者的子宫肌瘤体积平均缩小了47.80%(P<0.05)。其中E2、FSH、LH和P水平治疗后有所下降(P<0.01),其中较为显著的是E2和P;FSH和LH变化不明显。结论:米非司酮作为一种保守的治疗方式,对于治疗子宫肌瘤具有较好的临床疗效。
Objective: To observe the clinical effect of mifepristone in treating uterine fibroids. Methods: 60 patients with uterine fibroids admitted to our hospital were treated with oral mifepristone. The specific dosage was 10mg / time, once / d for 3 months. Before and after comparing patients with medication, ultrasound and ultrasound detection of uterine fibroids size. Results: After treatment, the clinical symptoms of 60 patients disappeared, hemoglobin returned to normal, and both have amenorrhea phenomenon. In 60 cases, the uterine volume was reduced by 40.80% (P <0.01), and the average volume of uterine fibroids was reduced by 47.80% (P <0.05). Among them, the levels of E2, FSH, LH and P decreased after treatment (P <0.01), of which E2 and P were more significant, and the changes of FSH and LH were not obvious. Conclusion: Mifepristone as a conservative treatment for the treatment of uterine fibroids have good clinical efficacy.