目的探讨膝关节内局灶型腱鞘巨细胞瘤的诊疗技术。方法1989年至2003年收治膝关节局灶型腱鞘巨细胞瘤患者12例,术前误诊半月板损伤6例,膝关节慢性滑膜炎3例,仅有3例通过MR I检查获得确诊。全部病例均采用关节镜下肿瘤完整切除术。结果9例患者获得1~10年随访,临床症状消失,膝关节活动正常,X线检查未见异常,未见复发病例。结论膝关节镜下手术治疗腱鞘巨细胞瘤是较佳方法,术中行瘤组织周围扩大切除及肿瘤取出组织通道处刨削清理,是防止肿瘤复发的关键所在。 Objective To investigate the diagnosis and treatment techniques of focal type of giant cell tumor of tendon sheath in knee joint. METHODS: From 1989 to 2003, 12 cases of focal giant cell tumor of the tendon sheath were treated. 6 cases were misdiagnosed with meniscus injury before surgery, and 3 cases were with chronic synovitis of the knee. Only 3 cases were diagnosed by MR I examination. All cases were treated with arthroscopic complete tumor resection. Results Nine patients were followed up for 1 to 10 years. The clinical symptoms disappeared and the knee joint activity was normal. There was no abnormal X-ray examination and no recurrence was found. Conclusions Knee arthroscopic surgery for giant cell tumor of tendon sheath is a better method. It is the key to prevention of tumor recurrence.