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异名 Myonal 化学名 4′-乙基-2-甲基-3-(1-哌啶基)苯丙酮盐酸盐药效分类肌肉松弛药开发单位 (日本)卫材株式会社上市厂商 (日本)卫材株式会社1983年2月首次上市药理本品作用于中枢神经系统及血管平滑肌,产生骨骼肌松弛作用及血管扩张作用及增进血流,尚有止痛作用,因此能从多种途径阻抑肌紧张性亢进→循环不全→疼痛→肌紧张性亢进这一恶性循环。由于本品具有镇痛及抑制疼痛反射的作用,且使脑血管意外患者顺利进行随意运动,但无镇静催眠作用。药物动力学大鼠口服~(14)C标记的本品50 mg/kg,在消化道基本吸收完全,但血浆
Synonyms Myonal Chemical Name 4’-ethyl-2-methyl-3- (1-piperidinyl) propanone Hydrochloride Pharmacodynamic classification Muscle relaxant Development Unit (Japan) Eisai Co., Ltd. Listed Company (Japan) Eisai Co., Ltd. first listed in February 1983 Pharmacology This product acts on the central nervous system and vascular smooth muscle, resulting in skeletal muscle relaxation and vasodilation and increase blood flow, there are still analgesic effect, it can inhibit muscle from a variety of ways Tension hyperactivity → incomplete circulation → pain → hyperthyroidism this vicious cycle. As the product has analgesic and inhibit the role of pain reflex, and cerebrovascular accident patients smoothly exercise, but no sedative and hypnotic effects. Pharmacokinetic rat oral ~ (14) C marked this product 50 mg / kg, the basic absorption in the digestive tract completely, but the plasma