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固有淋巴细胞(innate lymphoid cells,ILC)是一种新近发现的具有获得性免疫功能的免疫细胞,它作为辅助性T细胞的“镜像细胞”而受到广泛关注。根据分泌细胞因子的不同,ILC被分为三个亚群,这些亚群在不同组织的免疫反应中分别发挥重要作用,并与疾病起始和进程相关。就ILC的命名分类、不同亚群的功能和相关疾病以及其发育分化过程分别进行综述。
Innate lymphoid cells (ILCs), a newly discovered immune cell with acquired immune function, have drawn much attention as “mirror cells” of helper T cells. Depending on the secreted cytokines, ILCs are divided into three subgroups that play important roles in the immune response of different tissues and are associated with the onset and progression of the disease. The classification of ILCs, the functions and related diseases of different subpopulations and the process of their development and differentiation are summarized respectively.