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目的:观察磁共振（MR）T2 mapping成像技术在布鲁菌性脊柱炎患者的应用，分析其特征性表现及定量性评价。方法:采用前瞻性临床研究方法，以2016年1月至2018年9月在新疆医科大学第一附属医院确诊的23例布鲁菌性脊柱炎患者为病例组，选择同期健康志愿者25例为对照组。使用磁共振成像（MRI）检查研究对象椎体，并自动生成T2 mapping图，在MR T2 mapping图上选择感兴趣区（ROI），自动生成T2 mapping值。对病例组患者病变椎体、临近未患病变椎体、椎旁脓肿与对照组椎体的T2 mapping值进行对比分析。结果:病例组共23例患者，其中男17例、女6例，年龄为（38.5 ± 13.4）岁；对照组共25例，其中男15例、女10例，年龄为（35.1 ± 12.7）岁。病例组23例患者中，病变累及5个胸椎、40个腰椎、7个骶椎，共52个椎体。其中有11个（21.2%）椎体MRI表现为骨髓水肿，41个（78.8%）椎体MRI表现为骨髓水肿与椎体骨质破坏并存。病例组病变椎体、临近未患病变椎体、椎旁脓肿和对照组椎体的T2 mapping值分别为（115.62 ± 11.37）、（75.21 ± 5.57）、（240.26 ± 30.67）、（77.29 ± 4.19）ms，病变椎体与临近未患病变椎体及对照组椎体的T2 mapping值比较差异有统计学意义（n t = 26.78、19.42，n P均< 0.05）。n 结论:MR T2 mapping检查技术可对布鲁菌性脊柱炎患者的病变组织进行量化评估，对其定量描述及定性诊断有一定的指导意义。“,”Objective:To analyze the characteristics and quantitative evaluation of n Brucella spondylitis patients by magnetic resonance T2 mapping.n Methods:A prospective clinical study was conducted to analyze the MRI data of 23 patients with brucellosis spondylitis diagnosed in the First Affiliated Hospital of Xinjiang Medical University from January 2016 to September 2018, and 25 healthy volunteers were selected as the control group. MRI was used to examine the vertebral bodies of the subjects, and T2 mapping map was automatically generated. Regions of interest (ROI) were selected on the T2 mapping map to generate T2 mapping values automatically. The T2 mapping values of diseased vertebrae, adjacent unaffected vertebrae, paravertebral abscess and healthy volunteers were analyzed.Results:Among 48 MRI examinees, 23 cases were n Brucella spondylitis, including 17 males and 6 females, aged (38.5 ± 13.4) years; 25 healthy volunteers, including 15 males and 10 females, aged (35.1 ± 12.7) years. In 23 patients with n Brucella spondylitis, 5 thoracic vertebrae, 40 lumbar vertebrae and 7 sacral vertebrae were involved, with a total of 52 vertebral bodies. Among them, 11 (21.2%) vertebral bodies showed bone marrow edema on MRI, 41 (78.8%) vertebral bodies showed bone marrow edema and vertebral bone destruction. T2 mapping values of the diseased vertebrae, adjacent unaffected vertebrae and paravertebral abscess in n Brucella spondylitis patients and normal vertebrae in healthy volunteers were (115.62 ± 11.37), (75.21 ± 5.57), (240.26 ± 30.67) and (77.29 ± 4.19) ms, respectively. There were significant differences between the diseased vertebrae in n Brucella spondylitis and adjacent unaffected vertebrae in n Brucella spondylitis, and there were significant differences between the diseased vertebrae in n Brucella spondylitis and normal vertebrae in healthy volunteers (n t = 26.78, 19.42, n P < 0.05).n Conclusion:Magnetic resonance T2 mapping can be used to evaluate the pathological tissues in n Brucella spondylitis patients, and it has certain guiding significance for the quantitative description and qualitative diagnosis.n