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目的探讨采用不同方法补充钙剂预防产后出血的有效性及产后出血与血钙的关系。方法选取在广饶县人民医院作正规孕期检查、足月分娩的正常初产妇1200例,随机分为3组。A组孕28周开始口服维D钙咀嚼片2片(每片含碳酸钙750 mg,相当于钙300 mg,VD 3100 U)每日1次,直至分娩;B组孕期不补充钙剂,临产后给予10%葡萄糖酸钙注射液10ml静脉注射;C组孕期和临产后均不补充钙剂。结果①A、B 2组临产后血钙浓度高于C组,与C组比较,差异有统计学意义(均P<0.01);产后出血量少于C组,差异有统计学意义(均P<0.01)。②血钙浓度≤1.35 mmol/L时,产后出血的发生率增加。结论孕期孕妇补充钙剂是必要的,分娩前补充钙剂量可有效减少产后出血量,减少产后出血发生率。当血钙浓度≤1.35 mmol/L时,与产后出血呈负相关性。
Objective To explore the effectiveness of different methods of calcium supplementation in preventing postpartum hemorrhage and the relationship between postpartum hemorrhage and serum calcium. Methods 1200 cases of normal primipara in normal pregnancy and full-term labor were selected in Guangrao County People’s Hospital and randomly divided into 3 groups. A group of pregnant 28 weeks began oral administration of vitamin D calcium chewable tablets 2 (each containing calcium carbonate 750 mg, equivalent to calcium 300 mg, VD 3100 U) once daily until childbirth; B group during pregnancy without calcium supplement, labor Given 10% calcium gluconate injection 10ml intravenous injection; C group during pregnancy and postpartum were not added calcium. Results ① The serum level of calcium after labor in A and B 2 groups was higher than that in C group, and the difference was statistically significant (P <0.01); the amount of postpartum hemorrhage was less than that in C group (P < 0.01). ② blood calcium concentration ≤ 1.35 mmol / L, the incidence of postpartum hemorrhage increased. Conclusion Pregnant women with calcium supplement during pregnancy are necessary. Supplementation of calcium dose before delivery can effectively reduce the amount of postpartum hemorrhage and reduce the incidence of postpartum hemorrhage. When the serum calcium concentration ≤ 1.35 mmol / L, and postpartum hemorrhage was negatively correlated.