论文部分内容阅读
目的研究头孢曲松联合阿奇霉素治疗社区获得性肺炎的有效性和安全性。方法选取2013年4月—2014年4月于北京市顺义区杨镇沙岭卫生院全科门诊接受治疗的社区获得性肺炎患者100例,随机分为对照组和观察组,各50例。对照组给予头孢曲松治疗,观察组给予头孢曲松联合阿奇霉素治疗,两组患者均以1周为1个疗程,连续治疗2个疗程后,比较两组患者的临床疗效和不良反应发生情况。结果对照组总有效率(74%)低于观察组(96%),不良反应发生率(18%)高于观察组(6%),差异有统计学意义(P<0.05)。结论头孢曲松联合阿奇霉素治疗社区获得性肺炎的疗效确切,且不良反应少,安全性较高。
Objective To study the efficacy and safety of ceftriaxone combined with azithromycin in the treatment of community-acquired pneumonia. Methods From April 2013 to April 2014, 100 patients with community-acquired pneumonia received general outpatient treatment at Shaling Hospital of Yangzhen, Shunyi District, Beijing were randomly divided into control group and observation group, 50 cases in each group. The patients in the control group were treated with ceftriaxone. The patients in the observation group were treated with ceftriaxone and azithromycin. The patients in both groups were given 1 course of treatment for 1 week. After two courses of continuous treatment, the clinical efficacy and adverse reactions of the two groups were compared. Results The total effective rate (74%) of the control group was lower than that of the observation group (96%), and the incidence of adverse reactions (18%) was higher than that of the observation group (6%) (P <0.05). Conclusions Ceftriaxone combined with azithromycin has definite curative effect on community-acquired pneumonia with less adverse reactions and higher safety.