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目的探讨对Ⅲa期非小细胞肺癌行以手术为主的综合治疗的疗效。方法回顾分析2000年1月至2003年12月间在我院以手术为主综合治疗的83例Ⅲa期非小细胞肺癌患者(手术组)的临床资料,选择同期33例非手术治疗的Ⅲa期非小细胞肺癌患者作为对照(非手术组),采用Kap lan-M e ier法计算生存率,比较两组的中位生存时间和1,2,3年的生存率。结果手术组中位生存时间为20.3个月,1,2,3年生存率分别为85%,70%和35%。非手术组中位生存时间为14.5个月,1,2,3年生存率分别为75%,33%和15%。结论对Ⅲa期非小细胞肺癌行以手术为主的综合治疗的疗效明显优于非手术的放射与化学治疗。
Objective To investigate the curative effect of comprehensive surgery-based treatment for stage Ⅲ a non-small cell lung cancer. Methods The clinical data of 83 patients with stage Ⅲ a non-small cell lung cancer (operation group) who underwent primary operation in our hospital from January 2000 to December 2003 were analyzed retrospectively. 33 cases of non-surgical treatment of stage Ⅲ a Non-small cell lung cancer patients as a control (non-surgical group), using Kaplan-Meier method to calculate the survival rate, the median survival time and 1, 2, 3-year survival rates were compared. Results The median survival time of the operation group was 20.3 months. The 1, 2, 3 year survival rates were 85%, 70% and 35% respectively. The median survival time in nonsurgical group was 14.5 months, and the 1, 2, 3-year survival rates were 75%, 33% and 15%, respectively. Conclusion The curative effect of comprehensive operation based on surgery in stage Ⅲ a non-small cell lung cancer is better than non-operative radiotherapy and chemotherapy.