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阿司匹林是临床上广泛应用的解热镇痛消炎抗风湿抗血小板聚集药．环境温度对其急性毒性的影响未见报道．本实验用孙氏改良寇氏法测定了不同温度下小鼠口服阿司匹林的ＬＤ５０，并对ＬＤ５０进行ｔ检验，发现低（１０－１２℃），中（１８－２０℃），高（２１－３１℃）温...
Aspirin is widely used in clinical antipyretic analgesic anti-inflammatory anti-rheumatoid anti-platelet aggregation drug. The impact of ambient temperature on its acute toxicity has not been reported. In this study, LD50 of oral aspirin was measured at different temperatures by Sun’s modified Korotkoff method, and LD50 was tested by t test. The results showed that low (10-12 ℃), moderate (18-20 ℃), high (21-31 ℃) temperature ...