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目的:本文主要是讨论研究十二指肠溃疡的临床治疗效果,观察三联给药与传统给药方案对于治疗十二指肠溃疡的临床效果差异。方法:选取我院收治的126例十二指肠溃疡患者,随机分为两组。对照组采用常规治疗方法质子泵抑制剂奥美拉唑以及阿莫西林治疗;观察组采用克拉霉素、甲硝唑以及奥美拉唑三联法进行治疗。结果:观察组总有效率为95.0%,治愈率43.3%,分别高于对照组的87.9%和25.0%,两组有显著性差异(P<0.01)。结论:三联法治疗十二指肠溃疡能取得满意的临床疗效,而且不良反应较小,患者耐受性较好,值得临床推广使用。
Objective: This article mainly discusses the study of clinical treatment of duodenal ulcer, to observe the clinical effect of triple therapy and traditional therapy for the treatment of duodenal ulcer. Methods: 126 cases of duodenal ulcer admitted in our hospital were randomly divided into two groups. The control group was treated with proton pump inhibitor omeprazole and amoxicillin by conventional treatment. The observation group was treated with clarithromycin, metronidazole and omeprazole triple therapy. Results: The total effective rate was 95.0% in the observation group and the cure rate was 43.3%, which was significantly higher than 87.9% and 25.0% in the control group, respectively (P <0.01). Conclusion: triple therapy for duodenal ulcer can achieve satisfactory clinical efficacy, and adverse reactions are small, patients with better tolerance, it is worth promoting the use of the clinic.