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卵巢癌死亡率居女性生殖系统恶性肿瘤之首,早期诊断困难,晚期患者治疗效果差,分子靶向药物成为近年的研究热点。目前许多靶向药物已经进入临床试验阶段,给卵巢癌特别是术后复发及化疗耐药患者的治疗带来新的希望。本文主要对单克隆抗体,酪氨酸激酶抑制剂等几种药物在卵巢癌的研究进行综述。
Ovarian cancer mortality ranks first in the female genital system malignancy, early diagnosis difficult, late treatment of poor patients, molecular targeted drugs has become a hot research in recent years. At present, many targeted drugs have entered the clinical trial phase, which brings new hopes for the treatment of ovarian cancer, especially postoperative recurrence and chemoresistant patients. This article mainly reviews the research of several drugs such as monoclonal antibody and tyrosine kinase inhibitor in ovarian cancer.