类风湿性关节炎是一种慢性疾病,症状为关节僵硬及发炎、脆弱、丧失可动性、畸形。研究此类疾病的有效方法是建立、研究并应用动物模型。因此,用动物模型研究人类疾病的有效性是动物模型选择的最重要的标准,但不同的动物模型具有不同的特点,应根据实验的要求选择适当的模型。 Rheumatoid arthritis is a chronic disease characterized by stiff and inflamed joints, weakness, loss of mobility and deformity. An effective way to study such diseases is to establish, study and apply animal models. Therefore, animal models to study the effectiveness of human diseases is the most important animal model selection criteria, but different animal models have different characteristics, should be based on experimental requirements to select the appropriate model.