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蛋白质组学是系统研究分子体系、亚细胞系、细胞、组织、器官乃至整体水平蛋白质组成及其活动规律的一门学科。蛋白质组学技术为开展肝病研究建立了新的技术平台,并已成功筛选出一些具有潜在应用价值的蛋白标记物,用于肝病诊断和预后判断,同时发现一些新的药物治疗靶点,为肝脏疾病的诊断和治疗带来了新的机遇。本文旨在介绍蛋白质组学的相关研究技术及其在肝脏疾病研究中的应用。
Proteomics is a discipline that systematically studies the composition of proteins and their activity patterns in molecular systems, subcellular lines, cells, tissues, organs and even the whole body. Proteomics has established a new technology platform for liver disease research and has successfully screened out some potentially useful protein markers for the diagnosis and prognosis of liver disease. At the same time, some new drug treatment targets were found, namely, the liver Disease diagnosis and treatment has brought new opportunities. This article aims to introduce proteomics research techniques and its application in the study of liver diseases.