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目的探讨采取适当的干预措施使某二级甲等专科医院住院患者的抗菌药物使用率及三代头孢菌素的用药频率降低的可行性。方法按10%-20%的比例随机抽查2004年6月份的出院病历,进行调查,针对发现的问题采取相应的干预措施,再调查干预后的2004年7月份的出院病历,比较指标的变化,检验干预结果。结果住院患者抗菌药物使用率由6月份的53.75%下降至7月份的47.5%,三代头孢菌素的用药频率由6月份的42.3%下降至7月份的20.4%。结论全面合理的干预措施使住院患者的抗菌药物使用率及三代头孢菌素的用药频率降低是可行的。
Objective To explore the feasibility of using appropriate interventions to reduce the use of antimicrobial agents and the frequency of third-generation cephalosporin inpatients in a Grade A hospital. Methods A random sample of 10% -20% of discharged patients’ medical records in June 2004 were selected for investigation. Relevant intervention measures were taken according to the problems discovered. Then the medical records of discharged patients in July 2004 after intervention were compared and the changes of indicators were compared. Test the results of the intervention. Results The inpatient antibiotic use rate dropped from 53.75% in June to 47.5% in July. The frequency of third-generation cephalosporin administration dropped from 42.3% in June to 20.4% in July. Conclusion Comprehensive and reasonable interventions make it feasible to reduce the use of antimicrobial agents and third-generation cephalosporins in hospitalized patients.