患者男性,50岁主诉乏力、烦渴多饮伴血糖升高3年。现病史患者3年前出现乏力、烦渴多饮,于外院被诊断为2型糖尿病,初诊时空腹血糖9.8mmol/L,糖化血红蛋白8.2%。当地医院给予二甲双胍和格列本脲治疗,前两年血糖控制尚可,近一年血糖控制逐渐变差,当前口服降糖药方案为二甲双胍500mg Tid,格列本脲5mg Bid,阿卡波糖50mg Tid,血糖控制仍不达标,糖化血红蛋白7.4%。患者自测空腹血糖波动 Male patients, 50-year-old chief complaint of fatigue, polydipsia thirsty drink with blood sugar increased 3 years. Current history of patients with fatigue 3 years ago, thirst, polydipsia, was diagnosed with type 2 diabetes in the outer court, the first diagnosis of fasting blood glucose 9.8mmol / L, HbA1c8.2%. The local hospital to give metformin and glyburide treatment, the first two years of blood sugar control is acceptable, the blood glucose control in the past year gradually deteriorated, the current oral hypoglycemic regimen metformin 500mg Tid, glyburide 5mg Bid, acarbose 50mg Tid, blood glucose control is still not up to 7.4% glycosylated hemoglobin. Patients self-test fasting blood glucose fluctuations