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目的探讨扩大壁细胞迷走神经切断术(EPCV)治疗十二指肠溃疡急性穿孔的效果。方法回顾性分析2002年1月至2006年10月29例十二指肠溃疡急性穿孔患者行扩大壁细胞迷走神经切断术治疗的临床资料。结果本组病例均临床治愈出院,其中21例获随访。Visick分级,Ⅰ级24例(82.9%);Ⅱ级3例(10.3%);Ⅲ级1例(3.4%);Ⅳ级1例(3.4%);Ⅰ级和Ⅱ级共占27例(93.2%)。十二指肠溃疡复发1例(3.4%)。结论规范化EPCV手术治疗十二指肠溃疡急性穿孔的术后复发率低,临床效果满意。因此,EPCV术是目前治疗十二指肠溃疡急性穿孔首选的术式。
Objective To investigate the effect of expanding parietal cell vagotomy (EPCV) on acute perforation of duodenal ulcer. Methods The clinical data of 29 patients with acute perforation of duodenal ulcer from January 2002 to October 2006 were retrospectively analyzed. Results The patients were cured and discharged, of which 21 cases were followed up. Visick grading, grade Ⅰ 24 cases (82.9%); grade Ⅱ in 3 cases (10.3%); grade Ⅲ in 1 case (3.4%); grade Ⅳ in 1 case (3.4% %). One case of duodenal ulcer recurrence (3.4%). Conclusion The standardized recurrence rate of EPCV for acute perforation of duodenal ulcer is low, and the clinical effect is satisfactory. Therefore, EPCV surgery is the preferred surgical treatment of acute perforation of duodenal ulcer.